Obviously, the human diet has become progressively more divergent from those of our ancestors. This maladaptive change became apparent with the Industrial Revolution and has been accelerating in recent decades. In conjunction with this discordance between our ancient, genetically determined biology and the nutritional pattern, in contemporary Western populations, many of the so-called diseases ...

AIM To study in vitro influence of mechanochemically activated (MA) doxorubicin (DOXO) and electromagnetic irradiation (EMI) on human lung carcinoma A-549 cells. METHODS Solid state DOXO was MA by input energy 20 W/g during 5 min. Tumor cells were exposed to 40 MHz EMI with power density 2 W/cm(2) at temperature 37 degrees C. RESULTS Particles of MA DOXO have sizes 10 time smaller than offi...

BACKGROUND Cholangiocarcinoma is a serious public health in Thailand with increasing incidence and mortality rates. The present study aimed to investigate cytotoxic activities of crude ethanol extracts of a total of 28 plants and 5 recipes used in Thai folklore medicine against human cholangiocarcinoma (CL-6), human laryngeal (Hep-2), and human hepatocarcinoma (HepG2) cell lines in vitro. MET...

Microscopic research of the whole and crushed Alcea rosea leaves on twenty microslides according to method described in State Pharmacopoeia Republic Belarus was carried out. out comparing with a closely related type medicinal plant, being officinal, Althaea officinalis. During microscopic anatomical diagnostic features allowing identify this plant or form were discovered studied. The main them ...

Maturation of adenovirus particles is markedly affected by proteolytic processing. The possibility for blocking the conversion of precursor structural core protein (preVII) into mature structure protein VII by officinal drugs -aminocaproic acid and ambenum has been demonstrated in Hep-2 cells infected with adenovirus. Proteolytic processing may be regarded as one of the targets for inhibiting a...